P.029 Limbic system involvement in absence seizures
نویسندگان
چکیده
منابع مشابه
Cholinergic Neurotransmission In Partial Limbic Seizures
Cholinergic Neurotransmission in Partial Limbic Seizures. Geoffrey Liu, Joshua E. Motelow, Wei Li, Qiong Zhan, Asht M. Mishra, Robert N. S. Sachdev, Abhijeet Gummadavelli, Zaina Zayyad, Hyun Seung Lee, Victoria Chu, John P. Andrews, Dario J. Englot, Peter Herman, Basavaraju G. Sanganahalli, Fahmeed Hyder, Hal Blumenfeld. Partial limbic seizures impair consciousness, but the mechanism of impairm...
متن کاملAbsence seizures in children.
INTRODUCTION About 10% of seizures in children with epilepsy are typical absence seizures. Absence seizures have a significant impact on quality of life. METHODS AND OUTCOMES We conducted a systematic review and aimed to answer the following clinical question: What are the effects of treatments for typical absence seizures in children? We searched: Medline, Embase, The Cochrane Library, and o...
متن کاملRole of the Y5 neuropeptide Y receptor in limbic seizures.
Neuropeptide Y (NPY) is an inhibitory neuromodulator expressed abundantly in the central nervous system that is suspected of being an endogenous antiepileptic agent that can control propagation of limbic seizures. Electrophysiological and pharmacological data suggest that these actions of NPY are mediated by G protein-coupled NPY Y2 and NPY Y5 receptors. To determine whether the NPY Y5 receptor...
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BACKGROUND AND PURPOSE The efficacy of retigabine (RGB), a positive allosteric modulator of K+ channels indicated for adjunct treatment of partial seizures, was studied in two adult models of kainic acid (KA)-induced status epilepticus to determine it's toleratbility. METHODS Retigabine was administered systemiclly at high (5 mg/kg) and low (1-2 mg/kg) doses either 30 min prior to or 2 hr aft...
متن کاملElectrically Induced Limbic Seizures: Preliminary Findings in a Rodent Model
In epilepsy, novel pharmacological and nonpharmacological treatment approaches are commonly assessed in model systems of acute motor and often generalized seizures. We developed a rodent model with short-term electrical stimulation of the perforant path resulting in stereotyped limbic seizures. Limbic structures play a major role in human intractable epilepsy. In 10 rats, single electrical 5-se...
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ژورنال
عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
سال: 2017
ISSN: 0317-1671,2057-0155
DOI: 10.1017/cjn.2017.114